1990-1994 Issued Patents
The following U.S. patents were issued to University of Virginia inventors in the first half of the 1990s:
1990 Issued Patents
| Issue Date | Patent No. | Patent Title | Inventor(s) |
| 02/20/90 | 4,902,296 | Use of Demineralized Bone Matrix in the Repair of Segmental Defects | Mark E. Bolander, Gary Balian |
| 02/27/90 | 4,904,472 | Use of Adenosine Antagonists in the Treatment of Bradyarrhythmias and Mechanical Dysfunction Associated with Cardiopulmonary Resuscitation | Luiz Belardinelli, Robert C. Wesley Jr. |
| 05/08/90 | 4,923,801 | Compositions and Methods for the Enrichment and Isolation of Campylobacter Pylori and Related Organisms from Biological Specimens and the Environment | Barry J. Marshall, Richard L. Guerrant |
| 06/12/90 | 4,932,944 | Intravenous Port Injection and Connector System | Janine C. Jagger, Richard D. Pearson, Patrice G. Guyenet |
| 07/10/90 | 4,940,055 | High-Resolution Spectral Signature of Human Arterial Plaque | Michael F. Brown |
| 07/31/90 | 4,945,478 | Noninvasive Medical Imaging System and Method for the Identification and 3-D Display of Atherosclerosis and the Like | Michael B. Merickel, Charles S. Carman, James R. Brookeman, John P. Mugler III, Carlos R. Ayers |
| 08/07/90 | 4,947,417 | Adjusting Arrangement for Radio-Diagnostic Equipment | Gary Hartwell |
| 08/21/90 | 4,950,069 | Eye Movement Detector with Improved Calibration and Speed | Thomas E. Hutchinson |
| 08/21/90 | 4,950,249 | Hypodermic Needle with Reclosable Safety Cap | Janine C. Jagger, Richard D. Pearson |
| 10/16/90 | 4,963,128 | Chest Tube and Catheter Grid for Intrathoracic Afterload Radiotherapy | Thomas M. Daniel, Seung S. Hahn |
| 10/23/90 | 4,964,927 | Aluminum-Based Metallic Glass Alloys | Gary J. Shiflet, S. Joseph Poon, Yi He |
| 10/23/90 | 4,965,271 | Method of Inhibiting the Activity of Leukocyte Derived Cytokines | Gerald L. Mandell, Gail W. Sullivan, William J. Novick |
| 11/20/90 | 4,971,783 | Tissue Processing for Immunofluorescence Microscopy | W. Kline Bolton, Robert M. Mesnard |
| 11/27/90 | 4,973,149 | Eye Movement Detector | Thomas E. Hutchinson |
| 12/25/90 | 4,980,379 | Use of Adenosine Antagonists in the Treatment of Bradyarrhythmias and Hemodynamic Depression Associated with Cardiopulmonary Resuscitation and/or Cardiovascular Collapse | Luiz Belardinelli, Robert C. Wesley Jr. |
1991 Issued Patents
| Issue Date | Patent No. | Patent Title | Inventor(s) |
| 01/22/91 | 4,987,121 | Erythropoietic Factor | Alex J. Baertschi, Eero Niskanen |
| 02/05/91 | 4,989,920 | Self-Damping Caster Wheel | James J. Kauzlarich, Colin A. McLaurin |
| 03/19/91 | 5,000,781 | Aluminum-Transition Metal Alloys Having High Strength at Elevated Temperatures | David J. Skinner, Paul A. Chipko, Kenji Okazaki |
| 04/02/91 | 5,003,979 | System and Method for the Noninvasive Identification and Display of Breast Lesions and the Like | Michael B. Merickel, Ann H. Adams, James R. Brookeman |
| 04/02/91 | 5,004,608 | Amebiasis Vaccine | Jonathan I. Ravdin, William A. Petri Jr. |
| 04/23/91 | 5,009,634 | Metabolic Catheter | Marc D. Feldman, Thomas C. Skalak, Luiz Belardinelli |
| 04/30/91 | 5,011,708 | Use of Radioactive Nickel-63 to Inhibit Microbially Induced Corrosion | James L. Kelly, Ralph J. Reda |
| 05/21/91 | 5,017,378 | Intraorgan Injection of Biologically Active Compounds Contained in Slow-Release Microcapsules or Microspheres | Terry L. Turner, Stuart S. Howards |
| 07/09/91 | 5,030,420 | Apparatus for Oxygen Determination | John R. Bacon, James N. Demas |
| 07/30/91 | 5,036,045 | Method for Increasing Growth Hormone Secretion | Michael O. Thorner |
| 08/27/91 | 5,043,321 | Adrenocorticotropin Release Inhibiting Factor | Alex J. Baertschi |
| 09/10/91 | 5,047,508 | Monoclonal Antibody to MHS-5: A New Probe for Sexual Assault Analysis | John C. Herr, Mark Sigman, William M. Sutherland |
| 12/24/91 | 5,075,290 | Use of Adenosine, Adenosine Analogs or Nucleoside Uptake Blockers, e.g. Dipyridamole, as Drug Treatments for Obstructive Sleep Apnea and Snoring | Larry J. Findley, Robert C. Wesley Jr., Luiz Belardinelli |
| 12/31/91 | 5,077,540 | Minimum Pulse Width Switching Power Amplifier | F. Joseph Keith, Eric H. Maslen |
1992 Issued Patents
| Issue Date | Patent No. | Patent Title | Inventor(s) |
| 02/25/92 | 5,090,464 | Maintenance-Free Vehicle and Cart Tire | James J. Kauzlarich, Colin Metherell |
| 02/25/92 | 5,091,596 | Method for Producing Chiro-Inositol | Alison Kennington, Joseph Larner, Cynthia Hill, Butler Stringfield, Giorgio Carta, Donald J. Kirwan |
| 03/17/92 | 5,096,906 | Method of Inhibiting the Activity of Leukocyte Derived Cytokines | Gerald L. Mandell, Gail W. Sullivan, William J. Novick |
| 06/16/92 | 5,122,603 | Purified Insulin Mediators and Purification Process for Same | Joseph Larner, Alison S. Kennington, Laura C. Huang, Tsung-ying Shen |
| 06/23/92 | 5,124,252 | In Vitro Test for Fecal Leukocytes | Richard L. Guerrant, Amelia G. Lee, William H. Cooper |
| 06/23/92 | 5,124,360 | Dietary Supplement for Insulin-Resistant Diabetics | Joseph Larner, Alison S. Kennington |
| 06/30/92 | 5,125,888 | Magnetic Stereotactic System for Treatment Delivery | Matthew A. Howard III, Marc Mayberg, M. Sean Grady, Rogers C. Ritter, George T. Gillies |
| 07/14/92 | 5,130,654 | Magnetolelastic Amorphous Metal Ribbon Gradiometer | Marc D. Mermelstein |
| 09/08/92 | 5,145,712 | Chemical Deposition of Diamond | William A. Jesser, Fred P. Doty |
| 11/03/92 | 5,161,235 | Field-Effect Compound Semiconductive Transistor with GaAs Gate to Increase Barrier Height and Reduce Turn-On Threshold | Michael Shur, KwyRo Lee |
| 11/17/92 | 5,163,333 | Back and Trunk Positioning and Shape Sensing Apparatus | Clifford E. Brubaker, Colin A. McLaurin |
1993 Issued Patents
| Issue Date | Patent No. | Patent Title | Inventor(s) |
| 01/19/93 | 5,180,663 | Immunochemical Assays for Human Amylase Isoenzymes and Related Monoclonal Antibodies, Hybridoma Cell Lines and Production Thereof | David Bruns, David Benjamin |
| 02/02/93 | 5,183,764 | Quantitative Analysis for Diabetic Condition Predictor Involving Chiro-Inositol | Alison S. Kennington, Joseph Larner |
| 03/23/93 | 5,196,429 | Method of Inhibiting the Activity of Leukocyte Derived Cytokines | Gerald L. Mandell, Gail W. Sullivan, William J. Novick |
| 03/23/93 | 5,196,430 | Method of Inhibiting the Activity of Leukocyte Derived Cytokines | Gerald L. Mandell, Gail W. Sullivan, William J. Novick |
| 04/20/93 | 5,204,703 | Eye Movement and Pupil Diameter Apparatus and Movement | Thomas E. Hutchinson, Kevin S. Spetz, Nirav R. Desai |
| 08/31/93 | 5,240,694 | Combined Antiviral and Antimediator Treatment of Common Colds | Jack M. Gwaltney Jr. |
| 09/14/93 | 5,245,282 | Three-Dimensional Magnetic Resonance Imaging | John P. Mugler III, James R. Brookeman |
| 09/28/93 | 5,248,956 | Electronically Controllable Resistor | Glenn S. Himes, Catherine Q. Xu, Bradford W. Holcombe |
| 11/09/93 | 5,260,429 | Purified DNA of the 170-kd Surface of Gal/GalNAc Adherence Lectin of Pathogenic E. Histolytica | William A. Petri Jr., Barbara J. Mann |
| 11/16/93 | 5,262,692 | Variable Voltage Switched Current Control | Ronald D. Williams, F. Joseph Keith |
| 11/23/93 | 5,264,418 | Hemolymphopoietic Growth Factors, Process for Purifying and Producing Hemolymphopoietic Growth Factors and Pharmaceutical Compositions Made Therefrom | Peter J. Quesenberry, Ian K. McNiece |
| 11/30/93 | 5,266,356 | Method for Increasing the Corrosion Resistance of Aluminum and Aluminum Alloys | Rudolph G. Buchheit Jr., Glenn E. Stoner |
| 12/21/93 | 5,272,058 | Diagnostic Methods for E. Histolytica | William A. Petri Jr., Jonathan I. Ravdin |
| 12/21/93 | 5,272,153 | Method of Inhibiting the Activity of Leukocyte Derived Cytokines | Gerald L. Mandell, Gail W. Sullivan, William J. Novick |
1994 Issued Patents
| Issue Date | Patent No. | Patent Title | Inventor(s) |
| 05/17/94 | 5,311,957 | Steering Linkage | Colin A. McLaurin, Kao-Chi Chung |
| 05/24/94 | 5,314,409 | Catheter for Esophageal Perfusion | Jerzy Sarosiek, Richard W. McCallum, Ravinder K. Mittal |
| 09/13/94 | 5,347,190 | Magnetic Bearing Systems | David W. Lewis, Robert R. Humphris, Eric H. Maslen, Paul E. Allaire, Ronald D. Williams, Steven W. Yates |
| 10/04/94 | 5,352,537 | Plasma Sprayed Continuously Reinforced Aluminum Base Composites | Santosh K. Das, Michael S. Zedalis, Paul S. Gilman |
| 10/11/94 | 5,355,042 | Magnetic Bearings for Pumps, Compressors and Other Rotating Machinery | David W. Lewis, Robert R. Humphris, Eric H. Maslen, Paul E. Allaire, Ronald D. Williams |
| 11/01/94 | 5,360,388 | Round Window Electromagnetic Implantable Hearing Aid | Jonathan H. Spindel, Paul R. Lambert, Roger A. Ruth |
| 11/22/94 | 5,366,896 | Robotically Operated Laboratory System | Keith S. Margrey, Robin A. Felder, James C. Boyd, J. William Holman, Jonathan H. Roberts, John Savory, Antonia Martinez |